Alessia D.
- Country
- Italy
- Department
- Cardiolovascular Science
Research Overview
Data & Insights
Has run more than one trial at 0 of 303 partner sites.
Specializations
Cardiovascular Medicine
She investigates Acute coronary syndrome and its impact on myocardial injury, while also exploring therapeutic strategies for heart failure with preserved ejection fraction and reduced ejection fraction. Her work addresses the pathophysiology of atherosclerotic cardiovascular disease and the prevention of thromboembolic complications.
- Acute myocardial infarction
- Heart failure with preserved ejection fraction
- Atherosclerosis progression
- Thromboembolic disease management
Clinical investigations are conducted at the Fondazione Policlinico Universitario Agostino Gemelli IRCCS, integrating cardiovascular imaging and biomarker analysis.
Metabolic Liver Disorders
Her research portfolio includes the study of Non‑alcoholic steatohepatitis (NASH) and its transition to advanced fibrosis, focusing on metabolic dysfunction‑associated steatohepatitis (MASH) and related cirrhosis.
- NASH progression and regression
- Liver fibrosis biomarkers
- Metabolic risk factor modulation
- Therapeutic impact on hepatic steatosis
She collaborates with hepatology units to evaluate non‑invasive imaging and serum markers for disease monitoring.
Oncologic Therapeutics
In the realm of cancer research, she contributes to trials targeting advanced solid tumors across multiple organ systems, emphasizing molecularly defined sub‑populations.
- HER2‑negative breast cancer
- Renal cell carcinoma
- Non‑small cell lung cancer
- Gastro‑esophageal adenocarcinoma
Her involvement includes patient selection based on genomic alterations and evaluation of targeted and immunotherapeutic agents.
Autoimmune and Inflammatory Disorders
She directs studies on systemic lupus erythematosus and related organ manifestations, as well as other autoimmune conditions such as rheumatoid arthritis and myasthenia gravis.
- Lupus nephritis treatment
- Rheumatoid arthritis disease activity
- Generalized myasthenia gravis
- Dermatomyositis management
Investigations integrate immunologic profiling and novel biologic therapies to modulate disease pathways.
Respiratory and Pulmonary Conditions
Her clinical focus includes severe respiratory diseases such as severe asthma with eosinophilic phenotype and chronic obstructive pulmonary disease, as well as acute vascular events in the lung.
- Eosinophilic asthma control
- Chronic obstructive pulmonary disease exacerbations
- Acute pulmonary embolism management
- Interstitial lung disease assessment
Collaborative work with pulmonology teams leverages functional testing and biomarker-driven therapeutic selection.
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