Alessandro P. P.
- Country
- Italy
- Department
- S.O.S. Cardiologia e Elettrofisiologia SMN
Research Overview
Data & Insights
Has run more than one trial at 11 of 15 partner sites.
Specializations
Oncology
Concentrates on the treatment of malignant neoplasms spanning common and rare tumour types.
- Breast cancer subtypes, including hormone‑receptor positive, HER2‑negative and triple‑negative disease
- Colorectal cancer in both early‑stage and metastatic settings
- Ovarian and fallopian tube neoplasms with focus on platinum‑sensitive and resistant disease
- Non‑small cell lung cancer incorporating targeted and immunotherapeutic approaches
- Rare sarcomas such as chondrosarcoma and leiomyosarcoma
Research includes novel agents, combination regimens and biomarker‑driven patient selection.
Cardiovascular Medicine
Addresses acute and chronic heart conditions, with an emphasis on arrhythmia and coronary disease.
- Atrial fibrillation management and anticoagulation strategies
- Acute coronary syndrome and reperfusion therapies
- Chronic coronary syndrome including long‑term secondary prevention
- Heart failure across reduced and preserved ejection fraction phenotypes
- Atherosclerotic cardiovascular disease in patients with end‑stage kidney disease
Efforts target risk reduction, device‑based interventions and outcome‑focused clinical evaluation.
Dermatology & Immune‑Mediated Skin Disorders
Focuses on inflammatory and autoimmune skin conditions with high unmet therapeutic need.
- Atopic dermatitis severity reduction and quality‑of‑life improvement
- Psoriasis, including generalized pustular and plaque forms
- Lupus erythematosus cutaneous variants, both acute and chronic
- Alopecia areata and severe hair loss management
- Hidradenitis suppurativa refractory disease treatment
- Vitiligo non‑segmental presentations
- Bullous pemphigoid targeted biologic therapy
Investigations emphasize biologics, small‑molecule inhibitors and patient‑reported outcomes.
Nephrology & Renal Diseases
Targets disorders of kidney function and associated systemic complications.
- Immunoglobulin A nephropathy disease progression and proteinuria control
- End‑stage kidney disease in patients undergoing dialysis
- Chronic kidney disease secondary to cardiovascular comorbidities
Research includes novel immunomodulatory agents and biomarkers of renal injury.
Infectious & Systemic Inflammatory Conditions
Encompasses viral infections and severe systemic immune responses.
- HIV‑1 infection in individuals on integrase inhibitor‑based regimens
- COVID‑19 and related coronavirus disease management
- Septic shock with personalized immunoglobulin therapy
Efforts aim to improve survival, reduce complications and optimize adjunctive therapies.
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