Alessandro I.
- Country
- Italy
- Department
- Oculistica
Research Overview
- Phase III Randomized Double‑Masked Sham‑Controlled Trial of Intravitreal IL6‑Mab in Patients with Uveitic Macular Edema
- Efficacy and Safety Evaluation of Izokibep in Patients with Non-infectious Intermediate, Posterior, or Pan-uveitis: A Phase 2b Randomized Controlled Trial
- A PHASE III, MULTICENTER, RANDOMIZED, DOUBLE MASKED, SHAM-CONTROLLED STUDY TO INVESTIGATE THE EFFICACY, SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF RO7200220 ADMINISTERED INTRAVITREALLY IN PATIENTS WITH UVEITIC MACULAR EDEMA
Data & Insights
Has run more than one trial at 14 of 50 partner sites.
Specializations
Retinal and Choroidal Disorders
Alessandro Invernizzi is involved in clinical research on age-related macular degeneration, geographic atrophy, diabetic macular edema, macular edema secondary to retinal vein occlusion, and uveitic macular edema, with additional interest in neovascular macular disease and polypoidal choroidal vasculopathy.
- Age-related macular degeneration
- Geographic atrophy
- Diabetic macular edema
- Uveitic macular edema
- Choroidal melanoma
His ophthalmic portfolio also includes persistent corneal epithelial defect and visual function preservation in retinal disease.
Inflammatory Bowel Disease and Immune-Mediated Gastroenterology
His research landscape includes ulcerative colitis, Crohn’s disease, and broader inflammatory bowel disease, with attention to treatment strategies in both pediatric and adult populations.
- Ulcerative colitis
- Crohn’s disease
- Moderately to severely active disease
- Endoscopic and transmural healing
- Therapeutic maintenance in IBD
This area reflects sustained involvement in immune-mediated intestinal disease and treatment optimization.
HIV and Antiviral Therapeutics
He is active in studies of HIV-1 infection, including treatment switching, virologic suppression, and long-acting antiretroviral strategies, as well as research in COVID-19 and mpox.
- HIV-1 infection
- Antiretroviral therapy
- Virologic suppression
- COVID-19
- Mpox virus disease
His antiviral interests extend to pediatric infectious disease and infection control in complex clinical settings.
Cardiovascular, Respiratory, and Renal Medicine
His clinical trial activity spans heart failure, recurrent pericarditis, atherosclerotic cardiovascular disease, chronic obstructive pulmonary disease, chronic kidney disease, and end-stage kidney disease.
- Heart failure
- Recurrent pericarditis
- Chronic obstructive pulmonary disease
- Chronic kidney disease
- Cardiovascular prevention
He also contributes to research in systemic inflammation and multisystem cardiometabolic disease.
Autoimmune, Hematologic, and Neuropsychiatric Conditions
His research interests include rheumatoid arthritis, juvenile idiopathic arthritis, immune thrombocytopenia, warm autoimmune hemolytic anemia, hereditary angioedema, and type 1 diabetes, alongside work in major depressive disorder, schizophrenia, obsessive compulsive disorder, and epileptic syndromes.
- Rheumatoid arthritis
- Immune thrombocytopenia
- Warm autoimmune hemolytic anemia
- Hereditary angioedema
- Major depressive disorder
His portfolio also reaches into neuroinflammatory disease and pediatric immune dysregulation.
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