Alessandra R.
- Country
- Italy
- Department
- Divisione di Ematologia
Research Overview
- (Summit) A Multi-Part, Randomized, Double-Blind, Placebo-Controlled Phase 2 Clinical Study of the Safety and Efficacy of CGT9486 in Subjects with NonAdvanced Systemic Mastocytosis
- Evaluation of Chemotherapy with Nivolumab in Early-Stage Classical Hodgkin Lymphoma with Low Metabolic Tumor Volume and Negative Interim PET
Data & Insights
Has run more than one trial at 5 of 53 partner sites.
Specializations
Hematologic Malignancies
Clinical research activity in acute leukemia, myeloproliferative neoplasms, and lymphoid cancers, with interest in both newly diagnosed and relapsed disease across adult and pediatric settings.
- Acute myeloid leukemia
- Acute lymphoblastic leukemia
- Multiple myeloma
- Follicular lymphoma
- Myelofibrosis
The therapeutic focus also includes chronic lymphocytic leukemia, mantle cell lymphoma, large B-cell lymphoma, and hairy cell leukemia.
Thoracic Oncology
Active involvement in studies of non-small cell lung cancer and small cell lung cancer, including biomarker-defined and advanced metastatic disease, with attention to treatment sequencing and perioperative management.
- Non-small cell lung cancer
- EGFR-mutated lung cancer
- KRAS G12C-mutant lung cancer
- Small cell lung cancer
- Head and neck squamous cell carcinoma
Additional interest extends to colorectal cancer, urothelial cancer, and other solid tumors requiring targeted or immunotherapeutic strategies.
Autoimmune and Inflammatory Disorders
Clinical trial involvement spans systemic autoimmune disease, inflammatory arthritis, and connective tissue disease, with emphasis on conditions affecting the skin, joints, and muscle.
- Atopic dermatitis
- Hidradenitis suppurativa
- Psoriatic arthritis
- Dermatomyositis
- Systemic lupus erythematosus
Research interests also include bullous pemphigoid, vitiligo, juvenile idiopathic arthritis, and Sjögren’s syndrome.
Neurology and Neuroimmunology
Research activity covers multiple sclerosis, Parkinson’s disease, and other disorders of the central and peripheral nervous system, with a therapeutic focus on immune-mediated and degenerative conditions.
- Multiple sclerosis
- Parkinson’s disease
- Myelin oligodendrocyte glycoprotein antibody-associated disease
- Chronic inflammatory demyelinating polyneuropathy
- Tourette’s disorder
Further interests include neurogenic orthostatic hypotension, multiple system atrophy, and radiologically isolated syndrome.
Pulmonary, Cardiovascular, and Rare Diseases
Clinical research also includes chronic respiratory disease, interstitial lung disease, and cardiovascular disorders, alongside selected rare diseases with unmet therapeutic need.
- Idiopathic pulmonary fibrosis
- Chronic obstructive pulmonary disease
- Asthma
- Atrial fibrillation
- AL amyloidosis
The portfolio further includes hereditary angioedema, systemic mastocytosis, and cardiomyopathy.
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