Alba S.
- Country
- Germany
- Department
- Innere Medizin I: Klinik für Endokrinologie, Diabetologie, Stoffwechsel und Klinische Chemie
Research Overview
- N1T-MC-MALO: A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes (SYNERGY-Outcomes); N1T-MC-TZ01 Tirzepatide in participants with high-risk MASLD; N1T-MC-RT01 Retatrutide in participants with high-risk MASLD
- Evaluation of Long-term Safety and Tolerability of Apraglutide in Patients with Short Bowel Syndrome-Intestinal Failure
Data & Insights
Has run more than one trial at 8 of 137 partner sites.
Specializations
Breast Cancer and Gastrointestinal Oncology
Clinical activity includes treatment strategies for hormone receptor-positive and HER2-negative breast cancer, as well as triple-negative breast cancer and HER2-positive disease. The oncology portfolio also extends to gastric cancer, gastroesophageal junction adenocarcinoma, colorectal cancer, pancreatic cancer, and biliary tract cancer.
- Metastatic breast cancer
- Early breast cancer
- Gastric and gastroesophageal junction cancer
- Colorectal and pancreatic malignancies
Research interests also cover molecularly selected solid tumors and perioperative or advanced-stage cancer care within the oncology setting.
Hematologic Malignancies and Cell Therapy
The investigator is involved in studies of acute myeloid leukemia, acute lymphoblastic leukemia, chronic myeloid leukemia, diffuse large B-cell lymphoma, mantle cell lymphoma, and multiple myeloma. This work also includes interest in myelodysplastic syndromes and other relapsed or refractory blood cancers.
- Acute leukemias
- Lymphoid malignancies
- Plasma cell disorders
- Gene-modified T-cell therapy
The clinical focus reflects engagement with transplant-related and immunotherapy-based approaches in hematologic disease.
Cardiovascular Disease and Cardiomyopathy
Research interests include heart failure, atherosclerotic cardiovascular disease, myocardial infarction, stroke prevention, and pulmonary arterial hypertension. The portfolio also covers hypertrophic cardiomyopathy, dilated cardiomyopathy, and transthyretin amyloid cardiomyopathy.
- Heart failure
- Acute coronary and cerebrovascular disease
- Amyloid cardiomyopathy
- Pulmonary arterial hypertension
Clinical work in this area also includes therapies targeting cardiovascular risk reduction and cardiorenal complications.
Renal Disease, Transplantation, and Metabolic Disorders
The investigator is engaged in studies of chronic kidney disease, IgA nephropathy, focal segmental glomerulosclerosis, Alport syndrome, and autosomal dominant polycystic kidney disease. Additional interests include kidney transplantation, renal allograft protection, and proteinuric glomerular disease.
- Glomerular disorders
- Kidney transplant care
- Chronic kidney disease
- Metabolic and endocrine kidney complications
Related clinical interests extend to diabetes, obesity, hyperlipidemia, and prediabetes, linking renal medicine with broader metabolic care.
Autoimmune, Inflammatory, and Rare Disease Therapies
Clinical research also spans ulcerative colitis, Crohn’s disease, psoriasis, atopic dermatitis, systemic lupus erythematosus, and rheumatoid arthritis. Additional therapeutic interests include amyloidosis, primary sclerosing cholangitis, and rare pediatric and genetic disorders.
- Inflammatory bowel disease
- Autoimmune skin and rheumatic disease
- Amyloid and hepatobiliary disease
- Pediatric rare disease
This area includes interest in immune-mediated and targeted therapeutic options across chronic inflammatory conditions.
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