Alba P. B.
- Country
- Spain
- Department
- Servicio de Hematologia
Research Overview
- Phase 1/2 Study of Subcutaneous Blinatumomab in Adults and Adolescents with Relapsed/Refractory or MRD+ B-cell Precursor Acute Lymphoblastic Leukemia
- A single arm, open-label Phase 3b study to describe the safety and tolerability of ivosidenib in combination with azacitidine in adult patients newly diagnosed with IDH1m acute myeloid leukemia (AML) ineligible for intensive induction chemotherapy ALIDHE
Data & Insights
Has run more than one trial at 14 of 101 partner sites.
Specializations
Hematologic Malignancies
This investigator is involved in clinical research across a broad range of hematologic malignancies, with activity spanning acute myeloid leukemia, myelodysplastic syndromes, lymphoma, and multiple myeloma. The portfolio also includes interest in relapsed or refractory disease settings and blood cancers defined by molecular or immunologic features.
- Acute myeloid leukemia
- Myelodysplastic syndromes
- Diffuse large B-cell lymphoma
- Multiple myeloma
- Chronic lymphocytic leukemia
Research activity extends to graft-versus-host disease and other transplant-related hematology domains.
Breast and Gynecologic Oncology
Clinical trial involvement includes breast cancer subtypes such as hormone receptor-positive, HER2-negative, HER2-positive, and triple-negative breast cancer, alongside advanced or metastatic disease. The investigator is also engaged in studies of ovarian cancer, endometrial cancer, cervical cancer, and related gynecologic malignancies.
- Hormone receptor-positive breast cancer
- HER2-positive breast cancer
- Triple-negative breast cancer
- Ovarian cancer
- Endometrial cancer
Work in this area reflects a strong focus on biomarker-defined and advanced solid tumor populations.
Thoracic and Gastrointestinal Solid Tumors
The investigator contributes to studies in non-small cell lung cancer, small cell lung cancer, head and neck squamous cell carcinoma, esophageal cancer, gastric cancer, colorectal cancer, pancreatic cancer, and biliary tract cancer. Research also covers advanced and metastatic solid tumors with molecular alterations relevant to targeted and immunologic treatment strategies.
- Non-small cell lung cancer
- Small cell lung cancer
- Head and neck squamous cell carcinoma
- Colorectal cancer
- Pancreatic cancer
Additional interest is evident in urothelial carcinoma, renal cell carcinoma, and other advanced solid tumors.
Autoimmune and Inflammatory Disorders
Clinical research activity includes systemic lupus erythematosus, lupus nephritis, rheumatoid arthritis, psoriatic arthritis, myasthenia gravis, and systemic sclerosis. The investigator is also involved in studies of immune-mediated conditions such as immune thrombocytopenia and graft-versus-host disease.
- Systemic lupus erythematosus
- Lupus nephritis
- Rheumatoid arthritis
- Myasthenia gravis
- Systemic sclerosis
This domain also encompasses inflammatory myopathies and other chronic immune dysregulation disorders.
Transplantation, Renal, and Cardiometabolic Medicine
The investigator’s trial portfolio includes kidney transplantation, antibody-mediated rejection, chronic kidney disease, IgA nephropathy, and other glomerular disorders. Additional areas include heart failure, atherosclerotic cardiovascular disease, obesity, type 2 diabetes, and sleep apnea, reflecting involvement in medically complex chronic disease management.
- Kidney transplantation
- Antibody-mediated rejection
- Chronic kidney disease
- Heart failure
- Type 2 diabetes
Research also extends to liver disease and cardiometabolic risk in advanced clinical settings.
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