Agnese M.
- Country
- Italy
- Department
- U.O.C. Gastroenterologia ed Endoscopia Digestiva
Research Overview
- A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Tulisokibart in Participants with Moderately to Severely Active Ulcerative Colitis
- Phase 3 Randomized Double-Blind Placebo-Controlled Study of Tulisokibart Efficacy and Safety in Moderately to Severely Active Crohn's Disease
- Efficacy and Safety Evaluation of Tulisokibart in Moderate to Severe Crohn's Disease: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Trial
Data & Insights
Has run more than one trial at 146 of 195 partner sites.
Specializations
Inflammatory Bowel Disease and Digestive Disorders
Clinical research activity includes ulcerative colitis, Crohn’s disease, and related intestinal inflammation, with attention to disease control and symptom relief in chronic gastrointestinal conditions.
- Ulcerative colitis
- Crohn’s disease
- Primary sclerosing cholangitis
- Cholestatic pruritus
- Eosinophilic esophagitis
The therapeutic profile also extends to bile acid diarrhoea, gastroparesis, and colorectal cancer within the gastroenterology setting.
Autoimmune and Immune-Mediated Disease
Investigational work covers myasthenia gravis, juvenile idiopathic arthritis, lupus nephritis, and other immune-driven disorders requiring targeted anti-inflammatory and immunomodulatory strategies.
- Generalized myasthenia gravis
- Juvenile idiopathic arthritis
- Lupus nephritis
- Primary immune thrombocytopenia
- Sjögren’s syndrome
Additional interest includes hidradenitis suppurativa, psoriasis, and atopic dermatitis, reflecting a broad focus on chronic immune-mediated inflammation.
Cardiovascular and Thromboembolic Disease
Research involvement includes atherosclerotic cardiovascular disease, atrial fibrillation, heart failure, and prevention of stroke and other major cardiovascular events.
- Acute myocardial infarction
- Atrial fibrillation
- Heart failure
- Cardiomyopathy
- Venous thromboembolism
Therapeutic interests also include pulmonary arterial hypertension, hypertension, and cardiac amyloidosis.
Respiratory and Allergic Disease
Clinical trial activity spans asthma, chronic obstructive pulmonary disease, pulmonary fibrosis, and other chronic respiratory disorders with inflammatory or eosinophilic features.
- Severe asthma
- COPD
- Idiopathic pulmonary fibrosis
- Pulmonary sarcoidosis
- Chronic rhinosinusitis with nasal polyps
Allergic disease interests also include seasonal allergic conjunctivitis, allergic rhinoconjunctivitis, and chronic spontaneous urticaria.
Oncology and Hematologic Malignancies
Research activity includes solid tumors and blood cancers, with emphasis on breast cancer, lung cancer, renal cell carcinoma, and lymphoma.
- Breast cancer
- Non-small cell lung cancer
- Renal cell carcinoma
- Multiple myeloma
- Myelodysplastic syndromes
Additional areas include hepatocellular carcinoma, urothelial carcinoma, colorectal cancer, and acute leukemia.
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