Agnès B.
- Country
- France
- Department
- Service d’Hépato-gastro-entérologie
Research Overview
Data & Insights
Has run more than one trial at 0 of 20 partner sites.
Specializations
Liver Cancer Therapeutics
The investigator concentrates on innovative treatments for hepatocellular carcinoma and related primary liver malignancies.
- Advanced HCC with vascular invasion
- Combination immunotherapy in unresectable liver tumors
- Targeted agents for MET‑exon 14 mutated liver cancer
- Adjuvant strategies after curative resection
Research is conducted within the multidisciplinary liver unit at CHU Grenoble Alpes.
Biliary Tract and Cholangiopathy
Focused on the clinical challenges of biliary tract cancer and associated cholestatic disorders.
- Therapeutic options for advanced cholangiocarcinoma
- Management of malignant biliary obstruction
- Precision medicine for FGFR‑altered biliary tumors
- Post‑operative care after biliary surgery
Collaboration with interventional radiology and hepatobiliary surgery enhances trial enrollment.
Chronic Liver Disease & Cirrhosis Management
Addresses the spectrum of chronic liver injury, including metabolic and autoimmune etiologies.
- Therapies for non‑alcoholic fatty liver disease
- Interventions in alcoholic hepatitis
- Disease‑modifying agents for primary biliary cholangitis
- Risk stratification in compensated cirrhosis
Patient pathways integrate hepatology, nutrition, and fibrosis assessment tools.
Gastrointestinal Oncology
Extends expertise to solid tumors of the digestive tract, notably colorectal and pancreatic cancers.
- Neoadjuvant regimens for locally advanced rectal cancer
- Targeted therapy for KRAS‑G12C mutant pancreatic adenocarcinoma
- Biomarker‑driven trials in metastatic colorectal disease
- Integration of radiologic response criteria in trial endpoints
Clinical coordination includes oncology, radiology, and surgical oncology services.
Liver Transplantation & Portal Hypertension
Specializes in peri‑transplant care and complications of portal hemodynamics.
- Optimization of immunosuppression after liver transplantation
- Management of portal hypertension in decompensated cirrhosis
- Pre‑emptive strategies for transplant‑related renal injury
- Evaluation of TIPS outcomes in refractory ascites
Trials are anchored in the transplant program of CHU Grenoble Alpes.
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