Aglaia K.
- Country
- Belgium
- Department
- Division of Endocrinology
Research Overview
- Long-Term Extension Study of Imeroprubart in Adult Patients With Graves' Disease
- Evaluation of Batoclimab Efficacy and Safety in an Open-Label Extension Study for Thyroid Eye Disease Treatment in Participants Completing IMVT-1401-3201/3202
- Phase 3 Randomized Quadruple-Masked Placebo-Controlled Trial of Batoclimab in Active Thyroid Eye Disease
Data & Insights
Has run more than one trial at 58 of 123 partner sites.
Specializations
Gastroenterology and Hepatology
Clinical research activity includes inflammatory bowel disease, Crohn’s disease, ulcerative colitis, and complex liver disease with interest in portal hypertension, cirrhosis, primary biliary cholangitis, chronic hepatitis D, and metabolic dysfunction-associated steatotic liver disease.
- Crohn’s disease
- Ulcerative colitis
- Cholangiocarcinoma
- Portal hypertension
- Metabolic liver disease
Work also extends to hepatocellular carcinoma, pancreatic cancer, and gastroenteropancreatic neuroendocrine tumors, reflecting a strong therapeutic focus on digestive and hepatobiliary disorders.
Cardiovascular and Pulmonary Vascular Disease
The investigator is involved in trials spanning pulmonary arterial hypertension, broader pulmonary hypertension, hypertrophic cardiomyopathy, heart failure, and atrial fibrillation, with additional attention to atherosclerotic cardiovascular disease and stroke prevention.
- Pulmonary arterial hypertension
- Hypertrophic cardiomyopathy
- Atrial fibrillation
- Heart failure
- Stroke prevention
Research interests also include pulmonary hypertension associated with interstitial lung disease and chronic obstructive pulmonary disease, linking cardiology with respiratory vascular care.
Autoimmune and Inflammatory Disorders
Clinical studies cover a wide range of immune-mediated conditions, including rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, psoriatic arthritis, hidradenitis suppurativa, and thyroid eye disease.
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Systemic sclerosis
- Hidradenitis suppurativa
- Thyroid eye disease
Additional involvement in myasthenia gravis, multiple sclerosis, and eosinophilic granulomatosis with polyangiitis highlights interest in both systemic and organ-specific immune disease.
Respiratory, Infectious, and Critical Care Medicine
Research activity includes severe asthma, idiopathic pulmonary fibrosis, progressive pulmonary fibrosis, chronic obstructive pulmonary disease, and interstitial lung disease, alongside acute conditions such as community-acquired pneumonia, COVID-19, and acute respiratory distress syndrome.
- Severe asthma
- Idiopathic pulmonary fibrosis
- COVID-19
- Acute respiratory distress syndrome
- Invasive fungal infection
The portfolio also includes mpox, RSV-associated disease, candidemia, and invasive aspergillosis, showing engagement with infectious diseases and severe hospital-based respiratory care.
Endocrine and Metabolic Medicine
Within the Division of Endocrinology, the investigator is active in studies of obesity, type 2 diabetes, type 1 diabetes, prediabetes, severe hypertriglyceridemia, and lipid disorders.
- Obesity
- Type 2 diabetes
- Type 1 diabetes
- Severe hypertriglyceridemia
- Thyroid eye disease
Further interests include Graves’ disease, vitiligo, and metabolic dysfunction-associated steatohepatitis, indicating a therapeutic focus that bridges endocrine, metabolic, and immune-related disease domains.
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