Radu V.

Focused on chronic liver disease complications, the investigator studies therapeutic interventions for portal hypertension in cirrhotic patients.

• Compensated cirrhosis due to viral hepatitis or non‑alcoholic steatohepatitis
• Decompensated cirrhosis with clinically significant portal hypertension
• Acute‑on‑chronic liver failure (ACLF) risk reduction
• Hemodynamic modulation to lower hepatic venous pressure gradient

Efforts target reduction of variceal bleeding and ascites formation.

The investigator’s portfolio includes chronic inflammatory disorders of the gut, such as ulcerative colitis and Crohn’s disease.

• Moderately to severely active ulcerative colitis
• Moderately to severely active Crohn’s disease
• Left‑sided ulcerative colitis evaluated with rectal therapy
• Maintenance strategies following induction remission

Therapeutic goals emphasize mucosal healing and sustained clinical remission.

In the field of airway disease, the investigator addresses severe asthma and allergy‑related conditions, including atopic dermatitis and chronic urticaria.

• Severe asthma uncontrolled on inhaled corticosteroid/long‑acting β2‑agonist therapy
• Chronic inducible urticaria subtypes (dermographism, cold, cholinergic)
• Moderate‑to‑severe atopic dermatitis requiring systemic therapy
• Seasonal allergic rhinitis driven by grass pollen exposure

Research seeks to enhance symptom control and reduce exacerbation frequency.

Additional interests involve rare immune and genetic disorders such as hereditary angioedema and iron‑overload disease.

• Acute attacks of hereditary angioedema treated with plasma‑derived C1‑esterase inhibitor
• Hereditary hemochromatosis linked to HFE gene mutations
• Immune modulation in chronic hepatitis B under nucleos(t)ide analogue therapy
• Prevention of cancer‑associated thrombosis in solid‑tumor patients

Efforts aim to provide disease‑specific therapeutic options and improve quality of life.