Adrian-Lucian B.
- Country
- Romania
- Department
- Ophthalmology Building, 1st floor, wards: 33, 34, 35
Research Overview
- Efficacy and Safety Evaluation of Efgartigimod PH20 SC in Adults with Bullous Pemphigoid: A Phase 2/3 Randomized, Double-Blind, Placebo-Controlled Study
- Efficacy and Safety Evaluation of Amlitelimab Monotherapy in Adults with Severe Alopecia Areata: A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study
- A multicenter, double-blind, randomized, placebo-controlled, parallel-group, twelve-week treatment proof-of-concept trial to explore the efficacy and safety of IDOR-1117-2520 in adults with moderate to severe chronic plaque psoriasis with or without psoriatic arthritis.
Data & Insights
Has run more than one trial at 7 of 67 partner sites.
Specializations
Dermatology and immune-mediated skin disease
Clinical research activity includes plaque psoriasis, psoriatic arthritis, prurigo nodularis, alopecia areata, and bullous pemphigoid, with additional involvement in dermatomyositis and cutaneous lupus phenotypes.
- Psoriasis and psoriatic arthritis
- Alopecia areata
- Bullous pemphigoid
- Prurigo nodularis
- Cutaneous lupus
Therapeutic interests extend across targeted control of inflammatory skin disorders and antibody-mediated dermatoses.
Rheumatology and systemic autoimmune disease
Investigator involvement is centered on rheumatoid arthritis, systemic lupus erythematosus, lupus nephritis, systemic sclerosis, Sjögren’s disease, and ANCA-associated vasculitis.
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Lupus nephritis
- Systemic sclerosis
- Sjögren’s disease
Work in this area also includes immune-mediated renal disease and broader connective tissue disease manifestations.
Gastroenterology and hepatology
Research interests cover ulcerative colitis, celiac disease, primary biliary cholangitis, chronic hepatitis B, non-alcoholic steatohepatitis, and cirrhosis with advanced hepatic dysfunction.
- Ulcerative colitis
- Celiac disease
- Primary biliary cholangitis
- Non-alcoholic steatohepatitis
- Cirrhosis
Therapeutic focus includes chronic inflammatory bowel disease and progressive liver disorders requiring advanced disease-modifying strategies.
Neurology, ophthalmology, and respiratory medicine
Clinical trial involvement includes multiple sclerosis across relapsing and progressive forms, myasthenia gravis, traumatic brain injury, and retinopathy of prematurity, alongside asthma, chronic obstructive pulmonary disease, and bronchiectasis.
- Multiple sclerosis
- Myasthenia gravis
- Traumatic brain injury
- Retinopathy of prematurity
- Asthma and COPD
These interests span neuroinflammatory disease, visual outcomes, and chronic airway inflammation.
Cardiometabolic and renal disease
Additional activity includes acute coronary syndrome, myocardial infarction, stroke, venous thromboembolism, type 2 diabetes, obesity, chronic kidney disease, and heart failure.
- Acute coronary syndrome
- Stroke
- Venous thromboembolism
- Type 2 diabetes
- Chronic kidney disease
Therapeutic emphasis is also seen in prevention of vascular events and management of metabolic-renal complications.
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