Adele C.
- Country
- Italy
- Department
- Pediatric and Rheumatologic and Immunology
Research Overview
- Safety, Tolerability, Pharmacokinetics, and Efficacy of Filgotinib in Children and Adolescents with Polyarticular-Course Juvenile Idiopathic Arthritis
- An Open-Label Randomized Trial Comparing Anakinra and Prednisone in Pediatric Colchicine-Resistant Recurrent Pericarditis
- Evaluation of Step-Up Versus Step-Down Therapeutic Strategies in Juvenile Idiopathic Arthritis Using Etanercept and Methotrexate Combination Therapy
Data & Insights
Has run more than one trial at 22 of 66 partner sites.
Specializations
Pediatric Rheumatology
Specializes in the investigation of innovative treatment approaches for juvenile idiopathic arthritis, with particular emphasis on personalized medicine strategies and treatment optimization protocols.
- Biomarker-guided therapy withdrawal
- Clinical remission assessment
- Subclinical inflammation monitoring
Focuses on developing evidence-based protocols for medication discontinuation in patients achieving sustained disease control.
Treatment Strategy Development
Evaluates comparative therapeutic approaches in childhood arthritis, examining both conventional and innovative treatment paradigms.
- Step-up therapeutic protocols
- Step-down intervention strategies
- Treat-to-target methodologies
Investigates the effectiveness of early aggressive intervention versus conventional treatment escalation approaches.
Biological Therapy Research
Conducts comparative studies of anti-TNF-alfa treatments in pediatric rheumatic conditions, focusing on biosimilar effectiveness and safety profiles.
- Biosimilar evaluation
- Treatment switching protocols
- Long-term safety monitoring
Examines the clinical outcomes of transitioning between originator biologics and biosimilar alternatives in pediatric patients.
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